Multiple Loci within the major histocompatibility complex confer risk of psoriasis

Bing-Jian Feng1, Liang-Dan Sun, Razieh Soltani-Arabshahi

  • 1Department of Dermatology, University of Utah School of Medicine, Salt Lake City, UT, USA.

Plos Genetics
|August 15, 2009
PubMed
Summary

This study identified two new genetic loci, C6orf10 and HLA-B, associated with psoriasis risk within the MHC region, beyond the known HLA-Cw*0602 allele. These findings enhance our understanding of psoriasis genetics and potential therapeutic targets.

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