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Pharmacovigilance

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Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
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Pascal's Law

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P-value

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The Quotient Rule

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Related Experiment Video

Updated: Jun 21, 2026

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy (PRRT): 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy (PRRT): 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods

Published on: April 24, 2020

[PSA--Quo vadis?].

C Börgermann¹, H Loertzer, H-J Luboldt

¹Klinik und Poliklinik für Urologie, Uroonkologie und Kinderurologie, Universitätsklinik, Hufelandstrasse 55, 45122, Essen, Germany. christof.boergermann@uk-essen.de

Der Urologe. Ausg. A

|August 15, 2009

Summary

This summary is machine-generated.

Early prostate cancer detection aims to find organ-confined cancers. The strategy may shift to identifying aggressive prostate cancers to avoid overtreatment.

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Quantification of Levator Ani Hiatus Enlargement by Magnetic Resonance Imaging in Males and Females with Pelvic Organ Prolapse

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Published on: April 17, 2019

Area of Science:

Oncology
Urology

Context:

Prostate cancer is the most common cancer in men.
Early detection is crucial for high cure rates in organ-confined disease.

Purpose:

To review current literature on early prostate cancer detection.
To discuss the paradigm shift towards identifying aggressive cancers.

Summary:

Annual screening for men aged 50+ is recommended, ending 10 years before life expectancy.
Digital rectal exam and prostate-specific antigen (PSA) tests are primary tools.
A PSA threshold of 4 ng/ml indicates a prostate biopsy; imaging plays a minor role.

Impact:

Current methods may lead to overtreatment of latent prostate cancers.
A revised approach focusing on aggressive cancer detection could mitigate overtreatment risks.