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Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
[Elective percutaneous coronary intervention after acute coronary syndrome]
Drazen Sebetić1, Miroslav Raguz, Ivana Sakić
1Cardiovascular Division, University Department of Medicine, Dubrava University Hospital, Zagreb, Croatia.
Insights
Elective percutaneous coronary intervention (PCI) is recommended for acute coronary syndrome (ACS) patients with persistent ischemia or significant blockages. PCI improves symptoms, exercise tolerance, and reduces residual ischemia, aligning with ESC and AHA/ACC guidelines.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
Context:
- Guidelines from the European Society of Cardiology (ESC) and American Heart Association/American College of Cardiology (AHA/ACC) define indications for elective percutaneous coronary intervention (PCI).
- PCI is a key therapeutic strategy following acute coronary syndrome (ACS).
Purpose:
- To outline the indications and success criteria for elective PCI in ACS patients based on current guidelines.
- To highlight the benefits of PCI in managing myocardial ischemia and coronary artery stenosis.
Summary:
- Elective PCI is indicated for ACS patients with ST-segment elevation myocardial infarction (STEMI) experiencing persistent ischemia or significant stenosis suitable for intervention.
- For non-ST-segment elevation ACS (NSTEMI), elective coronary angiography is recommended for low-risk patients with positive noninvasive ischemia tests, followed by PCI if indicated.
- PCI is also considered for non-culprit significant coronary artery stenosis identified during primary PCI for STEMI.
Impact:
- Successful PCI leads to earlier symptom resolution and improved clinical outcomes.
- PCI enhances patient effort tolerance and reduces the rate of residual ischemia detected by noninvasive tests.
- The success of PCI is evaluated through angiographic, clinical, and periprocedural assessments.
Abstract:
Elective percutaneous coronary intervention (PCI) after acute coronary syndrome (ACS), according to guidelines issued by the European Society of Cardiology (ESC) and American Heart Association/American College of Cardiology (AHA/ACC), is a therapeutic method that is indicated in patients with ACS with ST segment elevation in case of persistent signs of myocardial ischemia and with significant stenosis of coronary artery verified by coronary angiography, suitable for PCI according to the guidelines. It is also indicated for non-culprit significant stenosis of other coronary arteries which have been seen during primary PCI for ST segment elevation myocardial infarction (STEMI). After non ST segment myocardial infarction (NSTEMI) or after non-ST elevation ACS, elective coronary artery angiography is indicated in low risk patients if they have positive signs of ischemia on noninvasive tests. Depending on the results of coronary angiography, elective PCI is indicated according to ESC or AHA/ACC guidelines. The method success is assessed at three levels, i.e. by angiography, clinically and periprocedurally. PCI enables earlier and more efficient resolution of symptoms, better effort tolerance and lower rate of residual ischemia on noninvasive tests.
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