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Lasting reduction of postsurgical hyperalgesia after single injection of botulinum toxin type A in rat
Boris Filipović1, Lidija Bach-Rojecky, Zdravko Lacković
1Laboratory of Molecular Neuropharmacology, Department of Pharmacology and Croatian Brain Research Institute, University of Zagreb School of Medicine, Zagreb, Croatia.
Fundamental & Clinical Pharmacology
|August 18, 2009
Abstract:
A single injection of low doses of botulinum toxin type A (3.5 U/kg) completely abolished secondary mechanical hyperalgesia throughout its duration in a model of post surgical pain after gastrocnemius incision in rat.

