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Updated: Jun 21, 2026

Modifying Levels of Maternal Dietary Folic Acid or Choline to Study the Impact of Deficiencies on Offspring Health Outcomes
Published on: June 28, 2024
Diet and deprivation in pregnancy
Paul Haggarty1, Doris M Campbell, Susan Duthie
1Nutrition and Epigenetics Group, Rowett Institute of Nutrition and Health, University of Aberdeen, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK. p.haggarty@abdn.ac.uk
Socio-economic deprivation is linked to poorer pregnancy outcomes, with disadvantaged mothers having poorer diets and lower nutrient intake. Improving nutrition for these women could enhance pregnancy health and reduce birth inequalities.
Area of Science:
- Maternal and Child Health
- Nutritional Epidemiology
- Public Health
Background:
- Socio-economic deprivation is a known risk factor for adverse pregnancy outcomes.
- The specific role of nutrition as a mediator in this relationship requires further investigation.
Purpose of the Study:
- To investigate the association between socio-economic deprivation, nutritional status, and pregnancy outcomes in a UK cohort.
- To identify specific dietary patterns and nutrient deficiencies linked to deprivation and their impact on birth outcomes.
Main Methods:
- Prospective cohort study of 1461 singleton pregnancies in Aberdeen, UK (2000-2006).
- Assessed nutrient intake, supplement use, B vitamin and homocysteine status, birth weight, gestational age, neonatal treatment, and socio-economic deprivation.
- Statistical analysis adjusted for confounders like smoking, marital status, and parity.
Main Results:
- Deprived women were younger, less likely to take folic acid, and had diets low in protein, fiber, vitamins, fruits, and vegetables.
- Deprivation was associated with preterm birth and increased need for neonatal treatment.
- Low birth weight was linked to diets deficient in vitamin C, riboflavin, pantothenic acid, and sugars, even after adjusting for deprivation and other factors.
Conclusions:
- Pregnancy deprivation is associated with poor nutritional intake, contributing to health inequalities in pregnancy outcomes.
- Targeted nutritional interventions for disadvantaged women of childbearing age may improve pregnancy outcomes and reduce disparities.
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