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Updated: Jun 21, 2026
07:59
Acetylcholine Re-Challenge After Intracoronary Nitroglycerine Administration
Published on: April 4, 2022
A shot of adrenaline
Mays El-Dairi1, M Tariq Bhatti, Michael S Vaphiades
1Department of Ophthalmology, Duke University Eye Center and Duke University Medical Center, Durham, North Carolina 27710-3802, USA.
Survey of Ophthalmology
|August 18, 2009
Summary
Acute macular neuroretinopathy, a rare vision disorder, can cause sudden blind spots. This case study links its occurrence in a young woman to epinephrine administration.
Area of Science:
- Ophthalmology
- Neuroscience
Background:
- Acute macular neuroretinopathy (AMN) is a rare condition affecting young women, causing paracentral vision loss.
- Characterized by sudden, unilateral or bilateral scotomas with relative central vision sparing.
- Wedge-like macular lesions are a common clinical feature.
Observation:
- The exact etiology of AMN remains unknown, with proposed causes including viral, immunological, and vascular factors.
- No established treatments currently exist for AMN.
- Visual prognosis for patients with AMN is variable.
Findings:
- This report details a case of AMN in a young woman.
- The onset of AMN in this patient was associated with the administration of epinephrine.
- This association suggests a potential trigger or contributing factor for AMN.
Implications:
- This case highlights a potential link between epinephrine and acute macular neuroretinopathy.
- Further research is warranted to investigate the role of epinephrine in AMN pathogenesis.
- Understanding potential triggers could inform future diagnostic and therapeutic strategies for this rare condition.
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