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Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
Published on: January 9, 2015
Perfectionism and sensory phenomena: phenotypic components of obsessive-compulsive disorder
Jennifer C Lee1, Helena S Prado, Juliana B Diniz
1Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA. mariaceica.rosario@gmail.com
Background:
The aim of the study was to investigate how perfectionism and sensory phenomena (SP) interact as possible phenotypic components of obsessive-compulsive disorder (OCD).
Methods:
Forty-seven adult outpatients, meeting Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, criteria for OCD, and a control group of 41 community subjects were assessed using the Frost Multidimensional Perfectionism Scale (FMPS), the University of São Paulo-Sensory Phenomena Scale, and other standard measures of OCD severity.
Results:
Three of the FMPS subscales ("concern over mistakes," "doubts about action," and "parental criticism") were significantly different between OCD patients and control subjects. All subtypes of SP were significantly more frequent and more severe in OCD than in control subjects. The "incompleteness" subtype of SP was associated with high scores on all dimensions of the FMPS, whereas the "just-right" subtype of SP was only associated with "doubts about action," "personal standards," and "organization" subscales of the FMPS.
Conclusions:
Presence and severity of SP and specific elements of perfectionism clearly distinguish OCD patients from healthy control subjects. Some SP subtypes are associated with specific FPMS subscale scores, whereas others are not. These results emphasize the relevance of assessing different subtypes of perfectionism and SP in OCD patients as important subcomponents of the OCD phenotype.
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