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Quantitative Measurement of γ-Secretase-mediated Amyloid Precursor Protein and Notch Cleavage in Cell-based Luciferase Reporter Assay Platforms
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Single chain variable fragment against nicastrin inhibits the gamma-secretase activity

Ikuo Hayashi1, Sho Takatori1, Yasuomi Urano2

  • 1Department of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

The Journal of Biological Chemistry
|August 18, 2009
PubMed

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