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Related Concept Videos

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...

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Updated: Jun 20, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
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A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

Zinc and prostatic cancer.

Emily Ho1, Yang Song

  • 1Department of Nutrition and Exercise Science, Linus Pauling Institute, Oregon State University, 103 Milam Hall, Corvallis, Oregon 97330, USA. emily.ho@oregonstate.edu

Current Opinion in Clinical Nutrition and Metabolic Care
|August 18, 2009
PubMed
Summary
This summary is machine-generated.

High zinc levels are crucial for prostate health and may prevent prostate cancer. Research indicates zinc inhibits cancer development through various mechanisms, highlighting its protective role.

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Murine Prostate Micro-dissection and Surgical Castration
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Last Updated: Jun 20, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
07:25

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

Murine Prostate Micro-dissection and Surgical Castration
08:49

Murine Prostate Micro-dissection and Surgical Castration

Published on: May 11, 2016

Area of Science:

  • Oncology
  • Nutritional Biochemistry
  • Molecular Biology

Background:

  • The prostate gland has the highest zinc concentration among soft tissues.
  • Prostate cancer is associated with significantly decreased zinc levels.

Purpose of the Study:

  • To review current research on zinc's role in prostate cancer prevention.
  • To explore the mechanisms by which zinc influences prostate health and cancer development.

Main Methods:

  • Literature review of experimental and epidemiological studies.
  • Analysis of biochemical and cellular mechanisms of zinc action.

Main Results:

  • Experimental evidence strongly supports zinc's protective effect against prostate cancer.
  • Zinc inhibits key cancer pathways including oxidation, apoptosis, and NF-kappaB signaling.
  • Zinc is vital for maintaining DNA integrity and its transporters may act as tumor suppressors.

Conclusions:

  • Despite mixed epidemiological data, experimental findings indicate a significant protective role for zinc in the prostate.
  • Further in vivo research is needed to clarify zinc's interaction with prostate function.
  • Development of sensitive zinc biomarkers is crucial for future clinical studies.