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Updated: Jun 20, 2026

Preparation of Meiotic Chromosome Spreads from Mouse Oocytes for Assessment of Synapsis and Recombination
Published on: July 18, 2025
Analyzing mammalian female meiosis
Martha Susiarjo1, Carmen Rubio, Patricia Hunt
1School of Molecular Biosciences and Center for Reproductive Biology, Washington State University, Pullman, WA, USA.
Abstract:
The goal of this chapter is twofold: First, to acquaint the reader with the problems inherent in analyzing mammalian female meiosis and, second, to provide a step-by-step approach to mastering the necessary techniques. Although the methods presented are for use in the human and mouse, with subtle alterations the same techniques should be applicable to most mammalian species.
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