Related Experiment Video
Updated: Jun 20, 2026

04:42
Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
Are there developmentally limited forms of bipolar disorder?
David C Cicero1, Amee J Epler, Kenneth J Sher
1Department of Psychological Sciences, University of Missouri, Columbia, MO 65211, USA.
Journal of Abnormal Psychology
|August 19, 2009
Summary
Bipolar disorder may have limited forms, with high prevalence in young adults that often resolves by age 30. Further research is needed to confirm these findings and identify potential markers for distinct courses of the illness.
Area of Science:
- Psychiatry
- Epidemiology
- Developmental Psychology
Background:
- Bipolar spectrum disorders are traditionally viewed as chronic conditions.
- Emerging research suggests the possibility of developmentally limited forms of bipolar disorder.
- High prevalence rates in emerging adulthood warrant further investigation into the disorder's course.
Purpose of the Study:
- To investigate the prevalence and course of bipolar spectrum disorders in emerging adulthood.
- To explore the potential existence of developmentally limited forms of bipolar disorder.
- To identify factors that may differentiate between chronic and limited courses of bipolar disorder.
Main Methods:
- Analysis of two large, nationally representative epidemiological studies.
- Examination of prevalence rates of bipolar disorders across different age groups (18-24 and 25-29 years).
- Assessment of symptom endorsement and comorbid diagnoses across age groups.
Main Results:
- A high prevalence of bipolar disorders was observed in emerging adults (18-24 years: 5.5%-6.2%).
- Prevalence significantly decreased in the latter half of the third decade (25-29 years: 3.1%-3.4%).
- Symptom and comorbidity patterns showed minimal differences across age groups, indicating significant impairment in younger individuals.
Conclusions:
- The findings suggest a potential for developmentally limited forms of bipolar disorder, with spontaneous resolution in many cases.
- Ascertainment bias may partially explain the observed reduction in prevalence, but spontaneous resolution is also suggested.
- Longitudinal research is crucial to confirm the existence of these forms and identify distinguishing markers.
Related Concept Videos
Bipolar Disorder
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
Borderline Personality Disorder
Borderline Personality Disorder is a complex and multifaceted mental health condition characterized by pervasive instability in interpersonal relationships, self-image, emotions, and impulse control. This instability manifests in extreme emotional reactions, fear of abandonment, and self-destructive behaviors. The disorder significantly impacts daily functioning, often leading to distress in both personal and professional domains.
Genetic and Environmental Contributions
Borderline Personality...
Genetic and Environmental Contributions
Borderline Personality...
Mania and Antimanic Drugs: Overview
Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as a...
Oppositional Defiant Disorder
A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
Diagnostic Criteria and...
Depressive Disorders: MDD and Dysthymia
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
Conduct Disorder
Conduct disorder is a complex mental health diagnosis characterized by a repetitive and persistent pattern of behavior that violates societal norms, the rights of others, or age-appropriate rules. The diagnostic criteria for conduct disorder require the presence of at least three problematic behaviors within the past 12 months, with at least one occurring in the past six months. These behaviors are grouped into four categories: aggression toward people and animals; destruction of property;...