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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...

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Related Experiment Video

Updated: Jun 20, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
07:22

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

Extensive neonatal dermatophytoses.

Amol Metkar1, Anuja Joshi, Vishwanath Vishalakshi

  • 1Department of Dermatology, Rajiv Gandhi Medical College and Chhatrapati Shivaji Maharaj Hospital, Thane Municipal Corporation, Thane, Maharashtra, India. drmetkar@gmail.com

Pediatric Dermatology
|August 19, 2009
PubMed
Summary

A rare fungal infection, tinea corporis caused by Microsporum gypseum, affected a newborn. This case highlights an uncommon cause of extensive neonatal dermatophytoses.

Related Experiment Videos

Last Updated: Jun 20, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
07:22

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

Area of Science:

  • Dermatology
  • Mycology
  • Neonatal Medicine

Background:

  • Neonatal dermatophytoses are uncommon fungal infections affecting newborns.
  • Differential diagnoses for neonatal skin lesions include candidiasis and neonatal lupus erythematosus.
  • Microsporum gypseum is a geophilic dermatophyte, rarely implicated in human infections.

Observation:

  • A 25-day-old infant presented with widespread annular erythematous skin lesions.
  • Initial diagnostic considerations included fungal infection (candidiasis) and autoimmune conditions (neonatal lupus erythematosus).

Findings:

  • Investigations confirmed the diagnosis of tinea corporis.
  • The causative agent was identified as Microsporum gypseum, an uncommon pathogen for this condition.
  • This represents the first reported case of extensive neonatal dermatophytoses attributed to Microsporum gypseum.

Implications:

  • This case expands the known spectrum of dermatophytes causing neonatal infections.
  • Understanding the role of uncommon fungal agents is crucial for accurate diagnosis and treatment of neonatal skin conditions.
  • The potential influence of steroid exposure on the clinical presentation warrants further investigation.