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Updated: Jun 20, 2026
02:28
Measuring Psoriasis Severity at Home
Published on: March 1, 2024
Psoriasis and systemic inflammation: underdiagnosed enthesopathy.
1Section of Dermatology and Venereology, Department of Biomedical and Surgical Sciences, University of Verona, Verona, Italy. giampiero.girolomoni@univr.it
Summary
Psoriasis patients often have undiagnosed psoriatic arthritis (PsA) with early joint inflammation. Early detection of PsA in psoriasis patients can improve long-term outcomes.
Area of Science:
- Dermatology and Rheumatology
- Immunoinflammatory Diseases
Background:
- Psoriasis is increasingly recognized as a systemic disease beyond skin manifestations.
- Psoriasis is associated with a higher prevalence of comorbidities, including cardio-metabolic disorders and psoriatic arthritis (PsA).
- A shared underlying chronic systemic inflammatory state may link psoriasis and its comorbidities.
Purpose of the Study:
- To investigate the incidence of subclinical entheseal abnormalities in psoriasis patients.
- To evaluate the potential of early PsA detection in asymptomatic psoriasis patients for improved prognosis.
Main Methods:
- A prospective study comparing entheseal changes in clinically asymptomatic psoriasis patients with a control group.
- Ultrasonography was used to detect entheseal abnormalities.
Main Results:
- Psoriasis patients showed a significantly higher incidence of entheseal abnormalities compared to controls, despite lacking clinical arthritic symptoms.
- Higher baseline enthesitis scores in psoriasis patients correlated with more severe psoriasis outcomes.
- Subclinical enthesitis was detected in psoriasis patients, indicating early joint involvement.
Conclusions:
- Early detection of subclinical psoriatic arthritis (PsA) in psoriasis patients is feasible through ultrasonography.
- Identifying and managing early PsA signs in psoriasis patients may positively impact disease prognosis and clinical outcomes.
- Dermatologists play a crucial role in the early detection and management of PsA in psoriasis patients.
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