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Pathological changes in Fenneropenaeus indicus experimentally infected with white spot virus and virus morphogenesis
M Manjusha1, Resmy Varghese, Rosamma Philip
1National Centre for Aquatic Animal Health, School of Environmental Studies, Cochin University of Science and Technology, Lake Side Campus, Fine Arts Avenue, Kochi 682 016, India.
Journal of Invertebrate Pathology
|August 19, 2009
Summary
White spot virus infection causes significant pathological changes in Fenneropenaeus indicus, affecting organs like the gut and gills. Gill and foregut tissues show high infection rates, making them ideal for diagnosing white spot syndrome virus (WSV).
Area of Science:
- Aquatic animal pathology
- Viral disease diagnostics
- Shrimp aquaculture health
Background:
- White spot syndrome virus (WSV) is a major pathogen affecting penaeid shrimp globally.
- Understanding the pathological effects of WSV is crucial for disease management in aquaculture.
Purpose of the Study:
- To document the pathological alterations in Fenneropenaeus indicus experimentally infected with white spot virus.
- To identify specific tissues suitable for early diagnosis of WSV infection.
Main Methods:
- Experimental infection of Fenneropenaeus indicus with WSV.
- Histopathological examination using light and electron microscopy of various organs.
- Correlation of viral replication stages with observed pathological changes.
Main Results:
- Novel histopathological findings include gut lesions, hepatopancreatic tubule vacuolization, rectal pad necrosis, and gill arch vascular damage.
- Virus replication and morphogenesis were observed in infected tissues, particularly the crystalline tract of the eye.
- Gill and foregut tissues exhibited high infection levels at the onset of clinical signs.
Conclusions:
- WSV infection induces diverse and significant pathological changes in Fenneropenaeus indicus.
- Gill and foregut tissues are proposed as primary targets for routine WSV disease diagnosis due to early and high infection rates.
