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Vitamin D-resistant rickets type II-A, basal ganglia calcification, and catatonia: a casual or causal relationship?
André Russowsky Brunoni1, Ana C G Nakata, Teng Chei Tung
1correspondence and M.D., Institute of Psychiatry, University of São Paulo, Alameda Fernao Cardim 346/101 Postal Code: 01403-01020, São Paulo (SP), Brazil. brunowsky@gmail.com
Background:
Vitamin D-resistant rickets type-IIA (VDRR-IIA) is a rare, congenital, metabolic disorder characterized by hypocalcemia, rickets, and alopecia. There are reports correlating calcium-metabolic disorders with basal ganglia calcification (BGC) and neuropsychiatric symptoms.
Objective:
The authors document and discuss the relationships of these phenomena.
Method:
The authors describe a patient born with VDRR-IIA who subsequently developed BGC at age 15, and catatonic symptoms of progressive severity at age 16.
Results:
There appeared to be a positive correlation between the severity of BGC and neuropsychiatric symptoms.
Discussion:
This is the first time VDRR-IIA, BGC, and catatonia have been reported in a patient, and the authors discuss the relationship among the conditions.
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