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Published on: January 17, 2018
Pituitary adenoma: a radiotherapeutic perspective
Christopher S Platta1, Christopher Mackay, James S Welsh
1Department of Human Oncology, University of Wisconsin, Madison, USA.
American Journal of Clinical Oncology
|August 19, 2009
Summary
Pituitary adenomas are common brain tumors. This review covers their biology and management, focusing on radiotherapy for prolactinomas, Cushing disease, acromegaly, and nonsecretory adenomas.
Area of Science:
- Neuro-oncology
- Endocrinology
- Neurosurgery
Background:
- Pituitary adenomas represent 10-20% of CNS neoplasms, with autopsy studies suggesting up to 25% incidence.
- Treatment choice for pituitary adenomas depends on tumor type and patient symptoms.
Purpose of the Study:
- To review the biology of pituitary adenomas.
- To discuss current management principles for specific pituitary adenoma types.
- To emphasize published radiotherapeutic literature for pituitary adenomas.
Main Methods:
- Literature review of pituitary adenoma biology and treatment.
- Focused analysis of radiotherapeutic data for various adenoma subtypes.
Main Results:
- Management strategies vary significantly based on adenoma classification.
- Radiotherapy is a key modality for specific pituitary adenomas.
Conclusions:
- Comprehensive understanding of pituitary adenoma biology is crucial for effective management.
- Radiotherapy plays a significant role in treating prolactinomas, Cushing disease, acromegaly, and nonsecretory adenomas.
