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Imaging findings in pyogenic ventriculitis
Philippe G Jorens1, Maurits H Voormolen, Dominique Robert
1Department of (neurological) Critical Care Medicine, Antwerp University Hospital, University of Antwerp, Wilrijkstraat 10, B-2650 Edegem, Belgium. Philippe.Jorens@uza.be
Introduction:
Pyogenic ventriculitis is an uncommon but often severe intracranial infection.
Methods:
Case report with illustrative CT and MRI imaging.
Results:
A 49-year-old man presented with an intraparenchymal hematoma with extension of blood into the ventricles. The persistence of intraventricular blood necessitated long term placement of an external ventricular drain. On day 23 after admission, a contrast-enhanced CT scan of the brain showed slight hydrocephalus, irregular debris in the dependent part of the occipital horns and periventricular hypodensities. An MRI scan confirmed the characteristic hallmarks of pyogenic ventriculitis on the T2-weighted, Fluid Attenuated Inversion Recovery (FLAIR), and diffusion-weighted and contrast-enhanced T1-weighted images.
Conclusion:
Neuroimaging is crucial in clearly depicting pyogenic ventriculitis. A contrast-enhanced CT scan, but especially MR imaging, is an ideal tool to reliably diagnose this life-threatening cerebral infection.
Insights
Pyogenic ventriculitis, a severe brain infection, can be diagnosed using advanced neuroimaging. Magnetic resonance (MR) imaging is particularly effective in identifying this life-threatening condition.
Area of Science:
- Neurology
- Radiology
- Infectious Diseases
Background:
- Pyogenic ventriculitis is a rare yet severe intracranial infection.
- Early and accurate diagnosis is critical for patient outcomes.
Observation:
- A case report details a 49-year-old male with an intraparenchymal hematoma extending into the ventricles.
- External ventricular drain placement was necessary due to persistent intraventricular blood.
- Imaging revealed hydrocephalus, intraventricular debris, and periventricular hypodensities.
Findings:
- Contrast-enhanced computed tomography (CT) demonstrated signs suggestive of ventriculitis.
- Magnetic resonance (MR) imaging, including T2-weighted, FLAIR, diffusion-weighted, and contrast-enhanced T1-weighted sequences, confirmed the characteristic hallmarks of pyogenic ventriculitis.
Implications:
- Neuroimaging plays a crucial role in the diagnosis of pyogenic ventriculitis.
- MR imaging is an ideal tool for reliably diagnosing this life-threatening cerebral infection.
- Timely diagnosis via advanced imaging can guide appropriate treatment and improve prognosis.
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