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Beneficial effects of resistant starch on laxation in healthy adults
Kevin C Maki1, Lisa M Sanders, Matthew S Reeves
1Provident Clinical Research, Bloomington, Indiana and Glen Ellyn, Illinois, USA. kmaki@providentcrc.com
Objective:
This randomized, double-blind crossover trial evaluated the effects of a type 3 novel resistant starch (RS) versus wheat bran (WB) on faecal weight, frequency, and consistency in healthy adults.
Methods:
Following a 14-day baseline period during which subjects (n=14) consumed low-fibre (<2 g) test products, participants were assigned to receive 25 g RS or WB fibre daily for 14 days, then crossed over to the opposite treatment after a 7-day washout.
Results:
Daily faecal output increased from 128.8+/-68.7 g at baseline to 164.2+/-88.4 g with RS and 194.5+/-92.0 g with WB (both P<0.02 versus baseline). No significant differences among the three conditions were observed for bowel movement frequency. Faecal consistency ratings were increased with WB (P=0.001), but unchanged with RS.
Conclusions:
Dietary RS and WB increase faecal output in healthy adults.
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