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[Immunosuppression in hand transplantation: state of the art and future perspectives]

Robert Sucher1, T Hautz, G Brandacher

  • 1Medizinische Universität Insbruck, Abteilung für Allgemein-, Transplantations- und Thoraxchirurgie, Innsbruck, Austria. robert.sucher@i-med.ac.at

Handchirurgie, Mikrochirurgie, Plastische Chirurgie : Organ Der Deutschsprachigen Arbeitsgemeinschaft Fur Handchirurgie : Organ Der Deutschsprachigen Arbeitsgemeinschaft Fur Mikrochirurgie Der Peripheren Nerven Und Gefasse : Organ Der V
|August 19, 2009
PubMed

Avoidance or minimization of maintenance immunosuppression represents the key step for promoting wider applicability of reconstructive transplantation. Understanding the mechanisms of composite tissue allograft rejection is of essence in working towards this goal. We herein review the current knowledge on acute rejection in reconstructive transplantation and discuss findings in the light of novel immunosuppressive and immunomodulatory strategies.

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