Snake venom L-amino acid oxidases: some consideration about their functional characterization
Juliana P Zuliani1, Anderson M Kayano, Kayena D Zaqueo
1Laboratório de Bioquímica e Biotecnologia, Instituto de Pesquisas em Patologias Tropicais, Centro de Estudos de Biomoléculas Aplicadas à Medicina, Departamento de Medicina, Universidade Federal de Rondônia, Porto Velho-RO, Brazil.
Abstract:
Snake Venom L-amino acid oxidases (LAAOs E.C. 1.4.3.2) are flavoenzymes broadly found in various snake venom compositions. LAAOs have become an attractive subject for molecular biology, biochemistry, physiology and medicine due to their actions on various cells and biological effects on platelets, apoptosis, hemorrhage and others. In this review we try to summarize some of these reports, with special emphasis on apoptosis, anti-protozoa, bactericidal and anti-viral activities.
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