Brown recluse spider venom: proteomic analysis and proposal of a putative mechanism of action
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Lucilene D dos Santos1, Nathalia B Dias, José Roberto
1Laboratory of Structural Biology and Zoochemistry, CEIS/Dept. Biology, Institute of Biosciences of Rio Claro, São Paulo State University (UNES), Rio Claro, SP, Brazil.
Protein and Peptide Letters
|August 20, 2009
Abstract:
Loxosceles intermedia spider venom was subjected to proteomic analysis through a MudPIT shot-gun approach to identify the protein composition. Were identified 39 proteins which seem to responsible by the lesion of different types of tissues, to some physiopathological actions and by the prevention of structural damage to the toxin structures.
