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Related Concept Videos

The Retinoblastoma Gene01:20

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The Retinoblastoma Gene01:20

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Related Experiment Video

Updated: Jun 20, 2026

Live-3D-Cell Immunocytochemistry Assays of Pediatric Diffuse Midline Glioma
09:06

Live-3D-Cell Immunocytochemistry Assays of Pediatric Diffuse Midline Glioma

Published on: November 11, 2021

Trichoblastoma in a child.

Tae Wook Kang1, Hoon Kang, Hyung Ok Kim

  • 1Department of Dermatology, Kangnam St Mary's Hospital, Seoul, Korea.

Pediatric Dermatology
|August 20, 2009
PubMed
Summary

A benign skin tumor called trichoblastoma, typically seen in adults, is reported here in an 11-year-old girl. This rare pediatric case of trichoblastoma occurred independently of other skin conditions.

Area of Science:

  • Dermatology
  • Pediatric Oncology
  • Pathology

Background:

  • Trichoblastoma is a rare, benign neoplasm originating from follicular germinative cells.
  • It typically affects adults, most commonly between the fourth and sixth decades of life.
  • Presentation is usually a solitary nodule on the scalp, face, or perineum.

Observation:

  • This report details an unusual case of trichoblastoma.
  • The patient was an 11-year-old Korean girl presenting with a lesion on her right cheek.
  • This presentation is notable as trichoblastoma is extremely rare in childhood.

Findings:

  • The case represents a primary trichoblastoma in a pre-adolescent child.
  • This occurrence is outside the typical association with nevus sebaceous of Jadassohn.

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Live-3D-Cell Immunocytochemistry Assays of Pediatric Diffuse Midline Glioma
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Published on: November 11, 2021

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice
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Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice

Published on: August 4, 2011

  • This finding expands the known clinical spectrum of pediatric trichoblastoma.
  • Implications:

    • Highlights the importance of considering trichoblastoma in the differential diagnosis of pediatric facial tumors.
    • Suggests that trichoblastoma can occur in children independently of other congenital skin anomalies.
    • Contributes to the limited literature on pediatric trichoblastoma, aiding future diagnosis and management.