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Updated: Jun 20, 2026

Controlled Cortical Impact Model for Traumatic Brain Injury
Published on: August 5, 2014
Hypothalamic-pituitary axis deficiency following traumatic brain injury in a dog
Catherine Foley1, Kiko Bracker, Sharon Drellich
1Angell Animal Medical Center, Boston, MA 02130, USA. ce.foley@yahoo.com
Objective:
To describe endocrine dysfunction associated with traumatic brain injury in a dog.
Summary:
A 12-week-old dog presented with traumatic brain injury and did not respond to traditional supportive care. Continued hypothermia, electrolyte derangements, hypotension, and hyposthenuria prompted screening for and detection of several hypothalamic-pituitary disorders including: hypoadrenocorticism, central diabetes insipidus, hypothyroidism, and growth hormone deficiency. Electrolyte abnormalities, urine osmolarity, and blood pressure improved with treatment for the associated disorders.
New Or Unique Information Provided:
This is the first report of generalized hypothalamic-pituitary dysfunction or panhypopituitarism following traumatic brain injury in a dog.
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