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Postherpetic neuralgia in the elderly
1University of Bristol, Bristol, UK. r.w.johnson@bris.ac.uk
International Journal of Clinical Practice
|August 21, 2009
Summary
Postherpetic neuralgia (PHN) is a common complication of shingles, especially in the elderly. Vaccination against varicella zoster virus may prevent shingles and reduce PHN incidence and severity.
Area of Science:
- Geriatrics
- Infectious Diseases
- Neurology
Background:
- Postherpetic neuralgia (PHN) is the most frequent complication of herpes zoster (HZ), or shingles.
- The elderly are most commonly and severely affected by PHN, which significantly impacts quality of life.
Purpose of the Study:
- To review the epidemiology, clinical features, and management of PHN in the elderly.
- To explore the potential of varicella zoster virus (VZV) vaccination in preventing HZ and subsequent PHN.
Main Methods:
- Literature review focusing on PHN in elderly populations.
- Analysis of VZV vaccination strategies for HZ prevention.
Main Results:
- PHN is characterized by persistent pain after HZ rash resolution, often resistant to treatment.
- The elderly experience higher incidence and severity of PHN.
Conclusions:
- PHN poses a significant clinical challenge, particularly in older adults.
- Preventive strategies, including VZV vaccination, are crucial for reducing the burden of HZ and PHN.
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