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Related Concept Videos

Urodynamic Studies: Uroflowmetry01:19

Urodynamic Studies: Uroflowmetry

Uroflowmetry is a non-invasive urodynamic test designed to measure various aspects of urination, including volume, flow rate, and the time to void. This test is crucial for diagnosing and assessing conditions such as bladder outlet obstruction, bladder dysfunction, incomplete bladder emptying, incontinence, and urinary tract blockages caused by benign prostatic hyperplasia (BPH) and urethral strictures.Pre-Test Instructions:Before a uroflowmetry test, patients are typically advised to drink...
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Microbiota of the Urogenital Tract

The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...
Anatomy of the Genitourinary System II: Bladder and Urethra01:19

Anatomy of the Genitourinary System II: Bladder and Urethra

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Related Experiment Video

Updated: Jun 20, 2026

Vessel-sparing Excision and Primary Anastomosis
08:09

Vessel-sparing Excision and Primary Anastomosis

Published on: January 7, 2019

Early valve ablation can decrease the incidence of bladder dysfunction in boys with posterior urethral valves.

Mohamed Youssif1, Waleed Dawood, Samir Shabaan

  • 1Department of Urology, Main University Hospital, University of Alexandria, Alexandria, Egypt. dr.youssif@gmail.com

The Journal of Urology
|August 21, 2009
PubMed
Summary

Early valve ablation for posterior urethral valves significantly reduces bladder dysfunction in boys. Neonatal intervention promotes bladder healing and improves long-term outcomes compared to later treatment.

Related Experiment Videos

Last Updated: Jun 20, 2026

Vessel-sparing Excision and Primary Anastomosis
08:09

Vessel-sparing Excision and Primary Anastomosis

Published on: January 7, 2019

Area of Science:

  • Pediatric Urology
  • Neonatal Surgery
  • Bladder Dysfunction

Background:

  • Posterior urethral valves (PUV) can lead to severe bladder dysfunction, known as valve bladder syndrome.
  • Early intervention may offer a better chance for bladder recovery and improved function.

Purpose of the Study:

  • To test the hypothesis that early valve ablation decreases bladder dysfunction in boys with PUV.
  • To compare outcomes of neonatal valve ablation versus ablation after age 1 year.

Main Methods:

  • Retrospective study of 32 boys with PUV, divided into neonatal ablation (Group 1, n=16) and later ablation (Group 2, n=16).
  • Evaluated clinical, ultrasound, voiding cystourethrogram, and urodynamic parameters over a mean 3-year follow-up.
  • Assessed post-void residual urine, vesicoureteral reflux, bladder capacity, bladder compliance, and toilet training success.

Main Results:

  • Overall bladder dysfunction occurred in 12.5% of Group 1 vs. 50% of Group 2.
  • Neonatal ablation group showed significant improvement in post-void residual urine (87.5% vs. 62.5%) and resolution/improvement of vesicoureteral reflux.
  • Group 1 had significantly better mean cystometric bladder capacity and lower rates of hypocompliance and instability compared to Group 2.

Conclusions:

  • Neonatal valve ablation protects the bladder, promoting normal cycling and healing.
  • Early intervention is crucial for preventing long-term bladder dysfunction in boys with posterior urethral valves.
  • Highlights the importance of prenatal screening and specialized care for PUV.