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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
Scan quality effect on glaucoma discrimination by glaucoma imaging devices
K R Sung1, G Wollstein, J S Schuman
1UPMC Eye Center, Department of Ophthalmology, University of Pittsburgh School of Medicine, 203 Lothrop Street, Eye and Ear Institute, Suite 816, Pittsburgh, PA 15213, USA. schumanjs@upmc.edu
The British Journal of Ophthalmology
|August 21, 2009
Summary
Image quality within acceptable ranges does not impact glaucoma detection with GDx or HRT devices. However, Stratus OCT glaucoma discrimination is affected by image quality parameters.
Area of Science:
- Ophthalmology
- Medical Imaging
- Glaucoma Research
Background:
- Glaucoma diagnosis relies on ocular imaging technologies.
- Assessing the impact of image quality on diagnostic accuracy is crucial.
Purpose of the Study:
- To evaluate how image quality affects glaucoma detection capabilities across different imaging devices.
- To determine if manufacturer-recommended quality standards ensure consistent diagnostic performance.
Main Methods:
- Utilized data from the Advanced Imaging in Glaucoma Study (AIGS).
- Analyzed 104 healthy and 75 glaucomatous eyes imaged with GDx-VCC, HRT II, and StratusOCT.
- Employed logistic regression to model glaucoma classification based on image quality and discriminatory parameters.
Main Results:
- Image quality parameters were non-significant for GDx and HRT but inversely affected Stratus OCT predictions.
- Higher signal strength (SS) on OCT correlated with a lower probability of glaucoma.
- Age, ethnicity, and scan acquisition institute influenced OCT models.
Conclusions:
- Scan quality within acceptable limits does not influence glaucoma discrimination for GDx and HRT.
- Stratus OCT's ability to discriminate glaucoma is significantly affected by image quality.
- Further investigation into OCT image quality optimization is warranted.
