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Surreptitious drug use by patients in a panic disorder study
D B Clark1, C B Taylor, W T Roth
1Department of Psychiatry, Stanford University Medical Center, Calif.
The American Journal of Psychiatry
|April 1, 1990
Abstract:
In a double-blind, placebo-controlled trial comparing alprazolam and imipramine for panic disorder, serum analysis revealed that a substantial proportion of the patients took explicitly prohibited anxiolytic medication. Excluding these patients changed the results.