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Updated: Jun 20, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
Adjuvant endocrine therapy in post menopausal women: pharmacological evaluation using decision analysis approach in a
Yoshiko Miyazaki1, Ichiro Arakawa, Tadao Inoue
1Department of Pharmacy, Takatsu General Hospital, Takatsu-ku, Kawasaki City, Japan.
Abstract:
An optimal adjuvant endocrine therapy is yet to be established for post menopausal women with hormone receptor positive breast cancer. The current therapeutic options include initial, switch, and extended adjuvant therapies. We aimed to determine the most cost-effective therapeutic option using the clinical decision analysis method. It was suggested that aromatase inhibitor monotherapy in initial adjuvant therapy is the most cost-effective and optimal adjuvant endocrine therapy for post menopausal women with hormone receptor-positive breast cancer.
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