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Published on: November 18, 2018
Pulmonary artery aneurysms in Behçet's disease
Sema Yilmaz1, Kadriye Akar Cimen
1Division of Rheumatology, Selcuklu Faculty of Medicine, Selcuk University, Vatan cad. Devrim Sitesi B/Blok No: 25/4, Selcuklu, Konya, 42040, Turkey. drsemayilmaz@hotmail.com
Behçet's disease commonly causes pulmonary artery aneurysms, which can rupture. This case shows successful treatment and potential resolution of these rare, life-threatening vascular conditions with immunosuppressive therapy.
Area of Science:
- Vascular Medicine
- Rheumatology
- Cardiology
Background:
- Behçet's disease is a rare multisystem inflammatory disorder.
- Pulmonary artery aneurysms (PAAs) are a rare but life-threatening complication of Behçet's disease.
- PAAs have a high risk of rupture, necessitating prompt diagnosis and management.
Observation:
- A 30-year-old male with a 6-year history of Behçet's disease presented with chest pain, oral/genital ulcers, rash, weakness, and hemoptysis.
- Chest radiography revealed a suspicious opacity.
- Helical thoracic computed tomography (CT) angiography confirmed the presence of pulmonary aneurysms.
Findings:
- The patient's pulmonary aneurysms were successfully treated with a combination of colchicine, corticosteroids, and cyclophosphamide.
- This case highlights the potential for complete resolution of PAAs in Behçet's disease patients with appropriate immunosuppressive therapy.
- The findings underscore the importance of considering Behçet's disease in the differential diagnosis of pulmonary artery aneurysms.
Implications:
- Early diagnosis and aggressive immunosuppressive treatment can lead to favorable outcomes in patients with Behçet's disease-associated PAAs.
- This case contributes to the understanding of PAA management in Behçet's disease.
- Further research into the pathogenesis and optimal treatment strategies for PAAs in Behçet's disease is warranted.
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