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Updated: Jun 20, 2026

Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity
Published on: September 16, 2011
Coexistence of two types of allergic hypersensitivity to drugs
Joanna Glück1, Barbara Rymarczyk, Barbara Rogala
1Department of Internal Diseases, Allergology and Clinical Immunology, Medical University of Silesia, Zabrze, Poland. joagluck@mp.pl
Abstract:
Hypersensitivity to drugs is a complex diagnostic challenge. Detailed medical history remains the mainstay of drug hypersensitivity evaluation, which further determines diagnostic procedures, especially the types of skin tests to be performed. The current paper presents the case of a female patient with coexisting features of supposed immunoglobulin E (IgE) dependent allergic hypersensitivity to fluoroquinolones and those of non-IgE dependent allergic hypersensitivity to povidone-iodine. Hypersensitivity was diagnosed based on the appropriately selected skin tests.
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