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Histologic study of delayed reactions to coelenterates

G E Piérard1, B Letot, C Piérard-Franchimont

  • 1Department of Dermatopathology, University of Liège, Belgium.

We studied by immunohistochemistry three cases of delayed envenomation by coelenterates. The most prominent features were the grouping of human leukocyte antigen-DR-positive cells with Langerhans cells (S-100 positive) and helper/inducer T lymphocytes (Leu-1+, Leu-3+, and Leu-4+). This indicates the possibility of a type IV immunoreaction in the delayed cutaneous lesions caused by coelenterates.

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