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Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Updated: Jun 20, 2026

Expansion of Human Peripheral Blood γδ T Cells using Zoledronate

Expansion of Human Peripheral Blood γδ T Cells using Zoledronate

Published on: September 9, 2011

Cutaneous gamma/delta T-cell lymphoma.

Richard Koch¹, Elaine S Jaffe, Christian Mensing

¹Eduard-Arning Clinic for Dermatology and Allergology Asklepios Klinik St. Georg, Lohmühlenstraße 5, Hamburg, Germany. ri.koch@asklepios.com

Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

|August 22, 2009

Summary

This summary is machine-generated.

Primary cutaneous gamma/delta T-cell lymphoma (GD-TCL) is rare and aggressive. Hematopoietic stem cell transplantation offers a promising therapeutic option for patients with this challenging lymphoma.

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Last Updated: Jun 20, 2026

Expansion of Human Peripheral Blood γδ T Cells using Zoledronate

Expansion of Human Peripheral Blood γδ T Cells using Zoledronate

Published on: September 9, 2011

Expansion and Enrichment of Gamma-Delta (γδ) T Cells from Apheresed Human Product

Expansion and Enrichment of Gamma-Delta (γδ) T Cells from Apheresed Human Product

Published on: September 22, 2021

Area of Science:

Dermatology
Hematology
Oncology

Background:

Primary cutaneous gamma/delta T-cell lymphoma (GD-TCL) is a rare hematologic malignancy.
Fewer than 40 cases have been documented globally.
GD-TCL is characterized by aggressive behavior and poor prognosis, with a median survival of approximately 15 months.

Observation:

The study presents a case of a patient diagnosed with GD-TCL.
The patient initially underwent treatment with surgery, immunomodulatory therapy, and polychemotherapy.
The patient subsequently received allogeneic hematopoietic stem cell transplantation.

Findings:

The patient achieved complete remission following allogeneic stem cell transplantation.
This outcome suggests a potential benefit of this intensive therapeutic approach.

Implications:

Allogeneic stem cell transplantation may represent a viable and promising therapeutic strategy for aggressive lymphomas like GD-TCL.
Further research and case studies are warranted to confirm the efficacy of this treatment modality for GD-TCL.
This approach could improve survival rates for patients with this rare and often fatal condition.