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[Perioperative interstitial brachytherapy for recurrent keloid scars]
1CRLCC Nantes-Atlantique, Nantes-St-Herblain, France. e-rio@nantes.fnclcc.fr
Summary
Low dose-rate (LDR) brachytherapy using Iridium-192 effectively treats recurrent keloid scars resistant to other therapies. This perioperative approach achieved 86% local control and good functional outcomes in patients.
Area of Science:
- Oncology
- Dermatology
- Radiotherapy
Context:
- Keloid scars are benign fibrous growths that can cause cosmetic and functional issues.
- Recalcitrant keloids often require multimodal treatment approaches.
- Perioperative brachytherapy is an emerging technique for managing complex scar conditions.
Purpose:
- To evaluate the efficacy of perioperative low dose-rate (LDR) brachytherapy with Iridium-192 (Ir-192) in treating keloid scars.
- To assess local control rates, functional outcomes, and cosmetic results in patients with resistant keloids.
Summary:
- A retrospective analysis of 73 keloids in 58 patients treated with surgical excision and early perioperative LDR brachytherapy was conducted.
- The median dose administered was 20Gy, with a median follow-up of 44.5 months.
- Local control was achieved in 86% of cases, with recurrence rates inversely proportional to scar length.
Impact:
- Perioperative LDR brachytherapy significantly reduces recurrence rates in keloids resistant to conventional treatments.
- The treatment offers good functional results and acceptable cosmetic outcomes.
- This technique provides a valuable therapeutic option for patients with challenging keloid scars.
