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Updated: Jun 20, 2026
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Cancer-Associated Fibroblasts from Mouse Mammary Tumors as Tools for Molecular and Computational Studies
Published on: July 3, 2025
Mammary fibromatosis
Katrina N Glazebrook1, Carol A Reynolds
1Department of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, USA. glazebrook.katrina@mayo.edu
AJR. American Journal of Roentgenology
|August 22, 2009
Summary
Mammary fibromatosis is a rare, benign breast tumor that often mimics cancer on imaging. Despite being benign, it can be locally aggressive and recur, sometimes requiring extensive surgery.
Area of Science:
- Radiology
- Pathology
- Oncology
Background:
- Mammary fibromatosis is a rare stromal tumor.
- It can present as a palpable, spiculated mass.
- Radiological appearance can suggest malignancy.
Purpose of the Study:
- To illustrate imaging findings of mammary fibromatosis.
- To correlate imaging with pathologic findings.
- To describe the clinical presentation.
Main Methods:
- Review of imaging findings.
- Pathologic correlation.
- Clinical presentation analysis.
Main Results:
- Mammary fibromatosis presents as a locally invasive tumor.
- Imaging findings can be suspicious for malignancy.
- MRI is valuable for assessing chest wall invasion.
Conclusions:
- Mammary fibromatosis is a benign, nonmetastasizing tumor.
- It is locally aggressive with high recurrence rates.
- Radical surgery may be needed for recurrent disease.
