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Gouty arthritis in acute cerebrovascular disease

Ya-Hui Lin1, Huan-Lin Hsu, Ying-Chih Huang

  • 1Department of Neurology, Chiayi branch, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan, ROC.

Cerebrovascular Diseases (Basel, Switzerland)
|August 22, 2009
PubMed

Insights

Gout attacks occur in 6.5% of acute stroke patients, often within 9 days of admission. This gouty arthritis complication can lead to longer hospital stays for stroke patients.

Area of Science:

  • Neurology
  • Rheumatology
  • Cardiology

Background:

  • Gouty arthritis is a metabolic disorder linked to cardiovascular disease.
  • Gout is a significant risk factor for acute myocardial infarction and cardiovascular mortality.
  • The frequency of gout attacks in acute stroke patients remains understudied.

Purpose of the Study:

  • To determine the frequency of gouty arthritis in hospitalized stroke patients.
  • To identify characteristics of gouty arthritis in stroke patients.
  • To assess the impact of gout on stroke patient outcomes.

Main Methods:

  • Retrospective analysis of 920 ischemic stroke patients admitted between 2002 and 2005.
  • Evaluation of gouty arthritis frequency and risk factors.
  • Comparison of risk factors and hospital stay duration between gout and non-gout groups.

Main Results:

  • Gouty arthritis was present in 6.5% of stroke patients.
  • Gout attacks typically occurred within 9 days of admission.
  • Independent risk factors for gout attack included gout history, high uric acid, and hypercholesterolemia.
  • Patients with gout had a significantly longer acute ward stay (17.17 vs. 14.01 days).

Conclusions:

  • Gout attacks are a notable complication in acute stroke patients.
  • Gouty arthritis in stroke patients is associated with extended hospitalizations.
  • Further research into managing gout during acute stroke is warranted.
Abstract

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