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Related Concept Videos

Biofilms01:29

Biofilms

Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
Microbiota of the Urogenital Tract01:28

Microbiota of the Urogenital Tract

The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...

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Related Experiment Video

Updated: Jun 20, 2026

Antibiotic Efficacy Testing in an Ex vivo Model of Pseudomonas aeruginosa and Staphylococcus aureus Biofilms in the Cystic Fibrosis Lung
09:26

Antibiotic Efficacy Testing in an Ex vivo Model of Pseudomonas aeruginosa and Staphylococcus aureus Biofilms in the Cystic Fibrosis Lung

Published on: January 22, 2021

[Chronic prostatitis and biofilm].

R Bartoletti1, T Cai

  • 1Dipartimento di Area Critica Medico-Chirurgica - Unita di Urologia, Universita degli studi di Firenze, Italy.

Le Infezioni in Medicina
|August 22, 2009
PubMed
Summary
This summary is machine-generated.

Inflammatory prostatic diseases, particularly bacterial prostatitis, are a significant health concern affecting men aged 20-50. Biofilm presence complicates diagnosis and treatment of this condition.

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Last Updated: Jun 20, 2026

Antibiotic Efficacy Testing in an Ex vivo Model of Pseudomonas aeruginosa and Staphylococcus aureus Biofilms in the Cystic Fibrosis Lung
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Published on: September 20, 2024

Area of Science:

  • Urology
  • Microbiology

Context:

  • Inflammatory prostatic diseases pose significant social and economic burdens.
  • Prevalence in European countries ranges from 11-14%, primarily affecting men aged 20-50.

Purpose:

  • To investigate the challenges in diagnosing and treating bacterial prostatitis.
  • To explore the role of intraglandular biofilm in disease presentation and therapeutic resistance.

Summary:

  • Bacterial prostatitis has a low documented prevalence (7-13%) potentially due to underutilization of diagnostic tests.
  • Intraglandular biofilm may lead to scarce bacterial expression in biological fluids, hindering accurate diagnosis.
  • Biofilm formation is implicated as a key factor in the difficulties encountered during diagnosis and antibacterial treatment of prostatitis.

Impact:

  • Highlights the need for improved diagnostic methods for bacterial prostatitis.
  • Suggests biofilm disruption as a potential therapeutic target for prostatitis.
  • Emphasizes the importance of understanding microbial communities in prostatic diseases.