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Related Concept Videos

Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Clinical Trials01:16

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Bioavailability Study Design: Healthy Subjects Versus Patients01:15

Bioavailability Study Design: Healthy Subjects Versus Patients

Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...

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Updated: Jun 20, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Web-based weight loss in primary care: a randomized controlled trial.

Gary G Bennett1, Sharon J Herring, Elaine Puleo

  • 1Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, Massachusetts, USA. gary.bennett@duke.edu

Obesity (Silver Spring, Md.)
|August 22, 2009
PubMed
Summary
This summary is machine-generated.

A 12-week web-based weight loss program in primary care led to significant weight loss compared to usual care. Higher website engagement correlated with greater weight loss, showing the intervention

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Multidisciplinary Approach to Obesity Management: A Case Report
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E-Patient Counseling Trial (E-PACO): Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

Published on: August 1, 2019

Area of Science:

  • Obesity research
  • Primary care interventions
  • Digital health

Background:

  • Limited evidence exists for effective, sustainable weight loss strategies in primary care settings.
  • Obesity and hypertension are significant public health concerns requiring accessible management solutions.

Purpose of the Study:

  • To evaluate the short-term efficacy of a web-based weight loss intervention for primary care patients with obesity and hypertension.
  • To assess participant retention and website utilization in a digital health weight loss program.

Main Methods:

  • A 12-week randomized controlled trial involving 101 primary care patients.
  • Intervention group received a comprehensive website with moderate-intensity weight loss content and four health coaching sessions.
  • Control group received usual care.

Main Results:

  • Intervention participants achieved significantly greater weight loss (-2.56 kg) at 3 months compared to usual care (0.28 kg).
  • High participant retention (84%) and website utilization were observed.
  • Greater weight loss was associated with higher frequency of website logins.

Conclusions:

  • Web-based weight loss interventions are efficacious and can be successfully implemented in primary care.
  • Moderate-intensity, digitally delivered weight management programs show promise for patients with obesity and hypertension.
  • Encouraging patient engagement with digital platforms is key to maximizing weight loss outcomes.