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Updated: Jun 20, 2026

Quantitative Analysis of Dietary Vitamin A Metabolites in Murine Ocular and Non-Ocular Tissues Using High-Performance Liquid Chromatography
Published on: December 27, 2024
GC-MS Analysis of beta-Carotene Ethenolysis Products and their Synthesis as Potentially Active Vitamin A Analogues
I Jermacz1, J Maj, J W Morzycki
1Institute of Chemistry, University of Bialystok, Al. Pilsudskiego 11/4, 15-443, Bialystok, Poland.
Abstract:
beta-Carotene ethenolysis under promotion of well-defined ruthenium catalysts were examined as a novel method of synthesis of vitamin A derivatives. Efficient reaction was promoted by the second-generation Hoveyda catalyst. The products of ethenolysis in positions C15-C15', C11-C12, and C9-C10 were detected, but cleavage of the C11-C12 double bond predominated. Even better regioselectivity at this position was observed for cross-metathesis between beta-carotene and functionalized alkenes.
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