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A centromere map of the X chromosome from trisomies of maternal origin
N E Morton1, B J Keats, P A Jacobs
1CRC Research Group in Genetic Epidemiology, Department of Community Medicine, Southhampton General Hospital, UK.
Annals of Human Genetics
|January 1, 1990
Abstract:
A centromere map is derived from XXX and XXY trisomies of maternal origin. Preliminary data suggest reduced recombination in the tetrads giving rise to mei I nondisjunction, but an excess of recombination in the pericentric region. As in Drosophila, multichiasmate tetrads may be more at risk of nondisjunction than nullochiasmate tetrads.