Small cell neuroendocrine carcinoma of the cervix: report of two cases

Small cell neuroendocrine tumor of the cervix is a rare malignancy with aggressive behavior. Metastases and recurrent disease are frequent and multimodal therapy is commonly used. Neoadjuvant or adjuvant chemotherapy should be combined with radiation therapy and surgery, even in early stages. Nevertheless, due to the low prevalence of these tumors, the best treatment has not yet been determined. Two cases of small cell neuroendocrine tumor of the uterine cervix are reported. We describe the clinical course, diagnostic methods and examine treatments applied and survival.