Related Experiment Video
Updated: Jun 20, 2026

19:53
Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer
Published on: March 1, 2015
[Dysfunction of multiple cranial nerves in cephalic tetanus--case report]
Mutsumi Fujii1, Mitsuhiko Hokari, Akiko Yokoyama
1Department of Neurosurgery, Nakano General Hospital.
Brain and Nerve = Shinkei Kenkyu No Shinpo
|August 25, 2009
Summary
Cephalic tetanus, a rare form of tetanus, can manifest as cranial nerve palsies following head trauma. Prompt treatment with antitetanus human immunoglobulin and antibiotics can lead to recovery without complications.
Area of Science:
- Neurology
- Infectious Diseases
Background:
- Tetanus is a serious bacterial infection that affects the nervous system.
- Cephalic tetanus is a rare form characterized by cranial nerve involvement, often following head or neck injuries.
Observation:
- A 77-year-old unvaccinated male presented with trismus, ptosis, and multiple cranial nerve palsies after head trauma.
- Initial neuroimaging was unremarkable, but symptoms suggested cephalic tetanus linked to an infected head wound.
Findings:
- The patient received wound debridement, intravenous and intrathecal antitetanus human immunoglobulin (AHI), and benzylpenicillin.
- Recovery was achieved without autonomic dysfunction or generalized tetanic spasms.
Implications:
- This case highlights the importance of considering cephalic tetanus in patients with cranial nerve palsies and head injuries.
- Early diagnosis and comprehensive treatment, including AHI, are crucial for favorable outcomes in cephalic tetanus.
Related Concept Videos
Tetanus
Tetanus is a life-threatening neurological disorder characterized by persistent muscle contractions and spastic paralysis. It is caused by Clostridium tetani, a motile, Gram-positive, rod-shaped, obligate anaerobe. These bacteria produce terminal endospores, giving them a distinctive “lollipop” or “tennis-racket” appearance. They thrive in anaerobic environments, such as those found in deep puncture wounds.Once introduced into the body, the spores germinate into vegetative cells. These cells...
Botulism
Botulism is a life-threatening neuroparalytic condition caused by botulinum neurotoxin, which is produced by the bacterium Clostridium botulinum, a Gram-positive, spore-forming, obligate anaerobe.In adults, the toxin enters the body in different ways: in foodborne botulism, the preformed toxin is absorbed in the intestine. In wound botulism, spores grow in injured tissue and release the toxin into the blood. Infant botulism differs mechanistically from adult forms. In infants, botulism commonly...
Cranial Nerves: Types Part I
Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves, with the first six being essential in sensory perception, motor control, and autonomic functions related to the head and neck.
Olfactory Nerve (Cranial Nerve I)
The olfactory nerve, or cranial nerve I, is unique as it is purely sensory and dedicated to the sense of smell. This nerve originates in the olfactory epithelium of the...
Olfactory Nerve (Cranial Nerve I)
The olfactory nerve, or cranial nerve I, is unique as it is purely sensory and dedicated to the sense of smell. This nerve originates in the olfactory epithelium of the...
Cranial Nerves: Overview and Anatomy
The cranial nerves are an important part of the complex network of nerves in the human body. These nerves emerge directly from the brain and are responsible for transmitting essential information between the brain and various parts of the head and neck. There are 12 pairs of cranial nerves, systematically numbered using Roman numerals from I to XII, beginning from the anterior and moving to the posterior of the brain. Each cranial nerve is uniquely identified by names that reflect its function...
Cranial Nerves: Types Part II
Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves. While the first six innervate the head and neck, the latter six nerves innervate the head and neck, as well as organs and tissues in the thoracic and abdominal cavities. They facilitate communication, expression, and autonomic control within the human body.
Facial Nerve (Cranial Nerve VII)
Cranial nerve VII, or the facial nerve,...
Facial Nerve (Cranial Nerve VII)
Cranial nerve VII, or the facial nerve,...
Diphtheria
Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
