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A Robust Polymerase Chain Reaction-based Assay for Quantifying Cytosine-guanine-guanine Trinucleotide Repeats in Fragile X Mental Retardation-1 Gene
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A Robust Polymerase Chain Reaction-based Assay for Quantifying Cytosine-guanine-guanine Trinucleotide Repeats in Fragile X Mental Retardation-1 Gene

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Fragile X syndrome. I. An overview on its genetic mechanism

B Barbe1, P Franke, W Maier

  • 1CNRS, URA 1957, Hôpital Pitié-Salpêtrière, Paris 75651 cedex 13, France; Service de Psychiatrie Adulte, Prof JF Allilaire, Hôpital Pitié-Salpêtrière, Paris 75651 cedex 13, France.

European Psychiatry : the Journal of the Association of European Psychiatrists
|August 25, 2009
PubMed

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Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
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Among mammals, the gender of an organism is determined by the sex chromosomes. Humans have two sex chromosomes, X and Y. Every human diploid cell has 22 pairs of autosomes and one pair of sex chromosomes. A human female has two X chromosomes, while a male has one X chromosome and one Y chromosome.
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