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Updated: Jun 20, 2026

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
07:51

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Published on: August 1, 2025

Cannabis, mind, and mirth.

F Ames1, D Castle

  • 1Department of Psychiatry, University of Cape Town, Cape Town, South Africa.

European Psychiatry : the Journal of the Association of European Psychiatrists
|August 25, 2009
PubMed
Summary
This summary is machine-generated.

The discovery of the brain

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Area of Science:

  • Neuroscience and Pharmacology
  • Cannabis Research

Background:

  • The discovery of the endogenous ligand for the cannabinoid receptor (CB1) and its genetic sequence provides a molecular basis for understanding cannabis effects.
  • Cannabis sativa has known psychomimetic properties, but the relationship between intoxication and mood requires further investigation.

Purpose of the Study:

  • To discuss the psychomimetic properties of Cannabis sativa in light of recent neurobiological discoveries.
  • To explore the complex relationship between cannabis intoxication and mood states.
  • To advocate for renewed research into acute cannabis encephalopathy.

Main Methods:

  • Literature review and theoretical discussion.
  • Integration of findings from molecular biology, pharmacology, and clinical observation.

Main Results:

  • Cannabis intoxication can significantly alter mood and perception.
  • Understanding cannabis effects is crucial given the discovery of its endogenous ligand and genetic sequence.

Conclusions:

  • Renewed study of acute cannabis encephalopathy is essential for advancing our understanding of consciousness.
  • Such research can illuminate the perceptual experiences of vulnerable populations, including children, the elderly, and patients with specific conditions.