Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Photoreceptors and Visual Pathways

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...

Psychological and Sociocultural Causes of Schizophrenia

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...

Schizophrenia

Schizophrenia

Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those diagnosed.

Biological Causes of Schizophrenia

Biological Causes of Schizophrenia

Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin studies.

Diabetic Retinopathy

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Abortion care over 20 weeks gestation: a psychosocial exploration of patient experiences at the Royal Women's Hospital, Victoria, Australia.

Reproductive health·2025

Same author

Clinicians' attitudes towards the undergraduate medical student syllabus in psychiatry.

Irish journal of psychological medicine·2025

Same author

Clinical features of patients who are admitted under different criteria of the Irish Mental Health Act 2001: a retrospective cohort study.

Irish journal of psychological medicine·2025

Same author

The impact of fluphenazine withdrawal: a mirror-image study.

Irish journal of psychological medicine·2024

Same author

Temporal Trends in Severe Brain Injury and Associated Outcomes in Very Preterm Infants.

Neonatology·2024

Same author

A comparison of rate and methods of probable suicide for 2 years pre and post the onset of the COVID-19 pandemic.

Irish journal of psychological medicine·2024

Search research articles

Related Experiment Video

Updated: Jun 20, 2026

A Rhodopsin Transport Assay by High-Content Imaging Analysis

A Rhodopsin Transport Assay by High-Content Imaging Analysis

Published on: January 16, 2019

Retinitis pigmentosa and schizophrenia.

C McDonald¹, P Kenna, T Larkin

¹Institute of Psychiatry, Department of Psychological Medicine, de Crespigny Park, London SE5 8AF UK; St John of God Hospital, Stillorgan, Co Dublin, Ireland.

European Psychiatry : the Journal of the Association of European Psychiatrists

|August 25, 2009

Summary

This study reports on schizophrenia and delusional disorder in patients with retinitis pigmentosa (RP). Potential links include genetics, sensory deprivation, brain disease, and retinoid issues, guiding future research.

Related Experiment Videos

Last Updated: Jun 20, 2026

A Rhodopsin Transport Assay by High-Content Imaging Analysis

A Rhodopsin Transport Assay by High-Content Imaging Analysis

Published on: January 16, 2019

Area of Science:

Ophthalmology
Psychiatry
Medical Genetics

Background:

Previous literature suggests a link between schizophrenia and retinitis pigmentosa (RP).
RP is a group of inherited eye diseases causing vision impairment.
Schizophrenia is a serious mental disorder affecting how a person thinks, feels, and behaves.

Purpose of the Study:

To describe cases of schizophrenia and delusional disorder in patients with RP.
To explore potential reasons for an association between RP and schizophrenia.
To guide future research into the etiology of these disorders.

Main Methods:

Case series describing four patients.
Review of literature on potential associations.
Exploration of etiological factors.

Main Results:

Two cases of schizophrenia and two cases of delusional disorder were observed in patients with RP.
Potential etiological factors discussed include shared genetic predisposition, sensory deprivation, coarse brain disease, and retinoid dysregulation.

Conclusions:

An association between RP and schizophrenia may exist.
Further research into neurochemistry and medical genetics is warranted.
Awareness of this association can inform future etiological studies.