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Updated: Jun 20, 2026

A Rhodopsin Transport Assay by High-Content Imaging Analysis
Published on: January 16, 2019
Retinitis pigmentosa and schizophrenia
C McDonald1, P Kenna, T Larkin
1Institute of Psychiatry, Department of Psychological Medicine, de Crespigny Park, London SE5 8AF UK; St John of God Hospital, Stillorgan, Co Dublin, Ireland.
Abstract:
There have been previous suggestions in the literature of a link between schizophrenia and retinitis pigmentosa (RP) or its associated syndromes. In this article, we describe two cases of schizophrenía and two cases of delusional disorder occurring in patients with RP. We explore possible reasons for an association between RP and schizophrenia including shared genetic predisposition, sensory deprivation, coarse brain disease and retinoid dysregulation. Awareness of an association may help to direct future research into the aetiology of these disorders, especially in the areas of neurochemistry and medical genetics.
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