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Updated: Jun 20, 2026
19:15
Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
[Ecstasy poisoning in a 10-month-old infant]
1Centre d'évaluation et d'information sur la pharmacodépendance (CEIP), hospices civils de Lyon, 162 avenue Lacassagne, Lyon cedex 03, France.
Summary
Accidental ecstasy (MDMA) poisoning in a 10-month-old infant caused significant cardiovascular and neurological symptoms. Prompt medical care led to a full recovery, highlighting the risks of pediatric drug exposure in domestic settings.
Area of Science:
- Pediatric Toxicology
- Emergency Medicine
- Clinical Case Reports
Background:
- Ecstasy (3,4-methylenedioxymethamphetamine) use is increasingly prevalent beyond recreational settings.
- The domestic environment poses a risk for accidental pediatric exposure to illicit substances.
- Pediatric ecstasy poisoning is rare, with limited case reports available.
Observation:
- A 10-month-old infant presented with acute behavioral disturbances, including restlessness, hypertonia, and repetitive movements.
- Clinical manifestations included significant tachycardia, hypertension, agitation, mydriasis, and nystagmus.
- Differential diagnoses such as febrile seizures, cranial trauma, and encephalitis were systematically excluded.
Findings:
- Urinary toxicological screening confirmed the presence of methamphetamine, the primary metabolite of MDMA.
- Gas chromatography/mass spectrometry identified MDMA and caffeine in the infant's urine.
- The infant experienced a complete clinical recovery by the following morning.
Implications:
- This case underscores the potential for severe accidental drug poisoning in infants due to evolving substance use patterns.
- Increased awareness is needed regarding the accessibility of ecstasy in domestic environments.
- Prompt emergency department evaluation and toxicological analysis are crucial for managing pediatric drug ingestions.
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