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Published on: August 1, 2013
Phylogenetic analysis of rubella viruses isolated in 2008 outbreak in Argentina
Laura E Valinotto1, Mariana Viegas, María Elina Acevedo
1Laboratorio de Virología, Hospital de Niños R. Gutiérrez, Buenos Aires, Argentina.
Background:
A rubella outbreak was recorded in Buenos Aires during 2008.
Objectives:
The objective of this communication is to present the genetic and phylogenetic analyses of wild-type RUBV circulating in Buenos Aires during the 2008 outbreak.
Study Design:
Throat swab samples collected from patients diagnosed with rubella between June 2008 and December 2008 were inoculated in cell culture and 23 isolates were sequenced.
Results:
Phylogenetic analysis of the WHO-recommended window (nt 8731-9469) of the E1 envelope glycoprotein was performed and all isolates clustered with the 2B genotype.
Conclusions:
Genotype 2B seems to be endemically circulating in the Southern cone of Latin America, thus causing recent outbreaks.

