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A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

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Does working while ill trigger serious coronary events? The Whitehall II study.

Hugo Westerlund¹, Mika Kivimaki, Jane E Ferrie

¹Stress Research Institute, Stockholm University, SE-106 91 Stockholm, Sweden. hugo.westerlund@stress.su.se

Journal of Occupational and Environmental Medicine

|August 25, 2009

Summary

Working while ill does not appear to trigger coronary heart disease. This study found no increased odds of coronary events for individuals working while unhealthy compared to those taking sick leave.

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Area of Science:

Occupational Health
Cardiovascular Epidemiology
Psychosomatic Medicine

Background:

Previous research links working while ill to increased coronary heart disease (CHD) risk.
The potential triggering effect of working while ill on acute cardiovascular events requires investigation.

Purpose of the Study:

To determine if working while ill acts as a short-term trigger for coronary events.
To examine the association between working while ill and the incidence of coronary events in an occupational cohort.

Main Methods:

A nested case-control study design was employed within an occupational cohort.
Sickness absences preceding a coronary event were analyzed for 133 cases and 928 matched controls.
Working while ill was defined as continuing work despite suboptimal self-rated health or psychological distress.

Main Results:

No statistically significant increased odds of coronary events were observed for individuals who worked while ill compared to unhealthy controls who took sick leave (OR = 0.62; 95% CI = 0.28 to 1.38).
The observed association remained non-significant after multiple adjustments for potential confounders.

Conclusions:

The study provides no evidence to support the hypothesis that working while ill is a short-term trigger for coronary events.
Further research may explore long-term effects or other mechanisms linking work and cardiovascular health.