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A cross-sectional study of blood pressure control in hypertensive patients in general practice (the I-TARGET study)
Brian Rayner1, Hermanus S Schoeman
1Division of Nephrology and Hypertension, University of Cape Town, South Africa. brian.rayner@uct.ac.za
Insights
Hypertension control rates in South Africa were 61.2%, but physician inertia and suboptimal guideline adherence were identified. Improving these factors is crucial for better blood pressure management in hypertensive patients.
Area of Science:
- Cardiology
- Public Health
- General Practice
Background:
- Hypertension control remains suboptimal despite available treatments.
- Physician inertia is a significant factor contributing to poor blood pressure control.
- This study investigated hypertension control levels and reasons for inadequate control in South Africa.
Purpose of the Study:
- To assess blood pressure control rates in South African general practices.
- To identify factors contributing to uncontrolled hypertension.
- To evaluate adherence to treatment guidelines.
Main Methods:
- A multi-centre, cross-sectional study involving 15 general practices in South Africa.
- Inclusion of 451 treated hypertensive patients over 18 years old.
- Data collection on patient demographics, comorbidities, treatment regimens, and blood pressure control.
Main Results:
- Overall, 61.2% of patients achieved the target blood pressure (< 140/90 mmHg).
- A significant proportion of patients (71.4%) had comorbidities, with 37.9% having multiple.
- Physician inertia was noted, with 22.9% of uncontrolled patients having no action plan and 39.4% advised only lifestyle changes.
Conclusions:
- Hypertension control rates in this South African cohort were comparable to other studies.
- Deficiencies include physician inertia and inconsistent application of guidelines.
- Optimizing treatment requires greater physician awareness and adherence to local and international guidelines.
Introduction:
Despite the availability of multiple effective antihypertensive drugs, hypertension control rates remain poor. The reasons for this are complex, but increasingly, physician inertia has been identified as a crucial factor. In this study we attempted to define the level of blood pressure (BP) control and reasons for not achieving control in a survey of selected general practices within South Africa.
Methods:
This was a multi-centre, cross-sectional disease study involving 15 selected general practices throughout South Africa. Treated hypertensive patients over 18 years old were eligible for inclusion. The study was approved by Pharma Ethics, and after informed consent, consecutive hypertensive patients at the participating general practice centres were included, with each centre enrolling 30 patients.
Results:
A total of 451 patients, from 15 sites in South Africa, were entered in the study. The mean age of the patients was 60.7 years, 56.3% were female and 15.7% were current smokers. The BP was reduced by 26.4/17.6 mmHg (p < 0.001) in 220 patients with a documented initial BP. Co-morbidities were present in 322 (71.4%) patients and overall, 37.9% had more than one co-morbidity. Lifestyle modification was not uniformly applied, with only 46.1, 59.6 and 56.8% receiving advice about weight loss, exercise and diet, respectively. Less than a third (30.7%) of patients were on monotherapy, 42.8% were on two drugs (25.9% on fixed-drug combination and 16.9% on free combination) and 26.5% were on more than two agents. Most (86.9%) practitioners used either international or local guidelines to determine target BP. Overall, 61.2% of patients were at goal (BP < 140/90 mmHg). If a stricter target BP
Conclusions:
Control rates were quite good in comparison with other surveys within and outside South Africa. However we were able to define several important deficiencies: there was evidence of physician inertia and also practitioners need to be more cognisant of local and international guidelines to optimise treatment.
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