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Pasteurella multocida infection, a rare cause of mycotic abdominal aortic aneurysm
1Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands. m.j.koelemaij@amc.uva.nl
Abstract:
A 64-year-old man was admitted with abdominal pain 6 weeks after treatment with intravenous flucloxacillin for cellulitis of his right leg. Urgent operation was necessary for a mycotic aneurysm of the abdominal aorta due to infection with Pasteurella multocida, a microorganism residing in the oral cavity of domestic animals that very rarely causes infection of native arteries or grafts. The aorta was repaired with a rifampin-coated tube graft. Despite postoperative duodenal perforation, abdominal Candida infections, wound dehiscence, and renal insufficiency, the patient is alive 1 year postoperatively.
Insights
A rare Pasteurella multocida infection caused a mycotic abdominal aortic aneurysm in a patient previously treated for cellulitis. The patient survived aortic repair with a specialized graft despite multiple postoperative complications.
Area of Science:
- Vascular Surgery
- Infectious Diseases
- Microbiology
Background:
- A 64-year-old male presented with abdominal pain six weeks post-intravenous flucloxacillin treatment for leg cellulitis.
- The patient's condition necessitated urgent surgical intervention.
Observation:
- A mycotic aneurysm of the abdominal aorta was diagnosed.
- The causative agent identified was Pasteurella multocida, a bacterium typically found in animal oral cavities.
- This microorganism rarely infects native arteries or vascular grafts.
Findings:
- The abdominal aorta was successfully repaired using a rifampin-coated tube graft.
- The patient experienced several postoperative complications including duodenal perforation, abdominal Candida infections, wound dehiscence, and renal insufficiency.
Implications:
- This case highlights the potential for rare pathogens like Pasteurella multocida to cause severe vascular infections.
- Successful management involved complex surgical repair and management of multiple comorbidities.
- The use of a rifampin-coated graft may have contributed to a positive outcome in a challenging clinical scenario.
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